BDBM50396529 CHEMBL2171127

SMILES Nc1ncnc2scc(-c3ccc(NC(=O)Cc4cc(F)ccc4F)cc3)c12

InChI Key InChIKey=OYPSWGQEIRWPRG-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50396529   

TargetEukaryotic translation initiation factor 2-alpha kinase 3(Human)
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50396529(CHEMBL2171127)Copy SMILESCopy InChI

Affinity DataIC50: 11nMAssay Description:Inhibition of GST tagged PERK cytoplasmic domain mediated EIF2alpha phosphorylationMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
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TargetAurora kinase B(Human)
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50396529(CHEMBL2171127)Copy SMILESCopy InChI

Affinity DataIC50: 58nMAssay Description:Inhibition of Aurora BMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy BDB DOIPubMed
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TargetTyrosine-protein kinase Lck(Human)
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50396529(CHEMBL2171127)Copy SMILESCopy InChI

Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL