BDBM50396538 CHEMBL2171145

SMILES Cc1ccc(CC(=O)N2CCc3cc(ccc23)-c2cn(C)c3ncnc(N)c23)cc1

InChI Key InChIKey=NEIQAGHTFXGFSZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50396538   

TargetEukaryotic translation initiation factor 2-alpha kinase 3(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50396538(CHEMBL2171145)
Affinity DataIC50: 17nMAssay Description:Inhibition of PERK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50396538(CHEMBL2171145)
Affinity DataIC50: 17nMAssay Description:Inhibition of GST tagged PERK cytoplasmic domain mediated EIF2alpha phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed