BDBM50396764 CHEMBL2172375

SMILES OC(=O)[C@H]1CC[C@@H](CC1)c1cc2cccnc2c(n1)-c1cccc(c1)C#N

InChI Key InChIKey=TWWNJXWEOLLKJT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50396764   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50396764(CHEMBL2172375)
Affinity DataIC50: 41nMAssay Description:Inhibition of human PDE4D-mediated [3H]CAMP hydrolysis after 30 to 60 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50396764(CHEMBL2172375)
Affinity DataIC50: 41nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50396764(CHEMBL2172375)
Affinity DataIC50: 93nMAssay Description:Inhibition of human PDE4B-mediated [3H]CAMP hydrolysis after 30 to 60 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50396764(CHEMBL2172375)
Affinity DataIC50: 160nMAssay Description:Inhibition of human PDE4A-mediated [3H]CAMP hydrolysis after 30 to 60 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed