BDBM50397908 CHEMBL2179521

SMILES O=C(N1CC2CNCC2C1)c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=OWQGYUFKEMELBK-UHFFFAOYSA-N

Data  2 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50397908   

LigandPNGBDBM50397908(CHEMBL2179521)
Affinity DataIC50: 7.80E+3nMAssay Description:Apparent antagonist activity at alpha4beta2 nAChR in human SH-EP1 cells assessed as inhibition of nicotine-induced calcium flux by calcium4-based FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397908(CHEMBL2179521)
Affinity DataEC50:  5.10E+4nMAssay Description:Agonist activity at alpha4beta2 nAChR in human SH-EP1 cells assessed as calcium flux by calcium4-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397908(CHEMBL2179521)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]nicotine from alpha4beta2 nAChR in human SH-EP1 cells after 2 hrs by liquid scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397908(CHEMBL2179521)
Affinity DataKi:  1.30E+4nMAssay Description:Displacement of [3H]epibatidine from human alpha7 nAChR expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed