BDBM50398251 CHEMBL2177883

SMILES Cc1ncc(CO)c2c(Nc3ccccn3)c(NCCC(=O)OC(C)(C)C)oc12

InChI Key InChIKey=RXBOHCRUCADRLY-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50398251   

TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50398251(CHEMBL2177883)
Affinity DataEC50:  7.64E+3nMAssay Description:Agonist activity at human TLR8 expressed in HEK293 cells assessed as induction of NF-kappaB activity by measuring extracellular secreted alkaline pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed