BDBM50398456 CHEMBL2179119

SMILES Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc2[nH]c(cc12)-c1ccccc1

InChI Key InChIKey=HFDJAPMETZJFMI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50398456   

TargetMitogen-activated protein kinase 14(Human)
University of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50398456(CHEMBL2179119)
Affinity DataIC50: 3nMAssay Description:Inhibition of p38alpha MAPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM50398456(CHEMBL2179119)
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant human GST-tagged wild type EGFR ( 668 to 1210 residues) cytoplasmic domain expressed in baculovirus expression system prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM50398456(CHEMBL2179119)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wild type EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed