BDBM50398648 CHEMBL2178104

SMILES O=Cc1ccccc1CN=Nc1nc(cs1)-c1ccccc1

InChI Key InChIKey=SFIBUTQUJKIITB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50398648   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
State Key Laboratory of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM50398648(CHEMBL2178104)
Affinity DataIC50: 110nMAssay Description:Inhibition of human DHODH expressed in Escherichia coli BL21(DE3) using L-dihydroorotate as substrate after 10 mins by DCIP dye reduction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
State Key Laboratory of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM50398648(CHEMBL2178104)
Affinity DataIC50: 365nMAssay Description:Inhibition of human DHODH (M30 to R360 residues) by DCIP dye based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed