BDBM50398781 CHEMBL2180020

SMILES CC(C)C1=NC(N=C1N)(c1ccccc1)c1cccc(c1)-c1cncnc1

InChI Key InChIKey=JBCUFKPVMAMCAR-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50398781   

TargetBeta-secretase 1(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50398781(CHEMBL2180020)Copy SMILESCopy InChI

Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human BACE1 using (europium)CEVNLDAEFK(Qsy7) as substrate incubated for 10 mins prior to substrate addition measured after 15 mins by T...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50398781(CHEMBL2180020)Copy SMILESCopy InChI

Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by IonWorks assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL