BDBM50399281 CHEMBL2180818::US9102622, 14.1

SMILES Oc1ccc(CCCCCCCS(F)(=O)=O)cc1

InChI Key InChIKey=DWVKNBPHGUTQCN-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50399281   

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Connecticut

US Patent
LigandPNGBDBM50399281(CHEMBL2180818 | US9102622, 14.1)
Affinity DataKi:  23nM ΔG°:  -10.8kcal/mole IC50: 98nMT: 2°CAssay Description:All compound solutions are made to a concentration of 10 mM in DMSO. To test the stability of the compounds in enzyme assay conditions, 25 nmoles of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetCannabinoid receptor 1(Rat)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50399281(CHEMBL2180818 | US9102622, 14.1)
Affinity DataKi:  163nMAssay Description:Displacement of [3H]CP-55,940 from CB1 receptor in rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50399281(CHEMBL2180818 | US9102622, 14.1)
Affinity DataIC50: 427nMAssay Description:Inhibition of recombinant human hexahistidine-tagged MGL expressed in Escherichia coli using AHMMCE as substrate after 15 mins by medium throughput f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Mouse)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50399281(CHEMBL2180818 | US9102622, 14.1)
Affinity DataKi:  698nMAssay Description:Displacement of [3H]CP-55,940 from mouse CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed