BDBM50399332 CHEMBL2180881::US9364459, E

SMILES COc1cc(cc(OC)c1OC)C1=C(C(=O)NC1=O)c1c[nH]c2cccnc12

InChI Key InChIKey=HAZVONJAIHMOQD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50399332   

TargetVascular endothelial growth factor receptor 2(Human)
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM50399332(CHEMBL2180881 | US9364459, E)
Affinity DataIC50: 373nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM50399332(CHEMBL2180881 | US9364459, E)
Affinity DataIC50: 1.52E+3nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM50399332(CHEMBL2180881 | US9364459, E)
Affinity DataIC50: 215nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM50399332(CHEMBL2180881 | US9364459, E)
Affinity DataIC50: 215nMAssay Description:Inhibition of GSK3betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM50399332(CHEMBL2180881 | US9364459, E)
Affinity DataIC50: 373nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed