BDBM50400315 CHEMBL2181312

SMILES Fc1cc2COCC=CCOCc3cc(Nc4nccc(n4)-c(c1)c2)ccc3OCCN1CCCC1

InChI Key InChIKey=KJOZOAQMGSIFNM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50400315   

LigandPNGBDBM50400315(CHEMBL2181312)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant FLT3 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400315(CHEMBL2181312)
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant JAK2 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400315(CHEMBL2181312)
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant TYK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400315(CHEMBL2181312)
Affinity DataIC50: 380nMAssay Description:Inhibition of recombinant JAK1 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed