BDBM50400316 CHEMBL2181087

SMILES COc1cc2Nc3nccc(n3)-c3cccc(COCC=CCOCc(c2)c1OCCN1CCCC1)c3

InChI Key InChIKey=KYEFPHMQFQFRLZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50400316   

TargetTyrosine-protein kinase JAK1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400316(CHEMBL2181087)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant JAK1 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400316(CHEMBL2181087)
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant JAK2 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400316(CHEMBL2181087)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant FLT3 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400316(CHEMBL2181087)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant TYK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed