BDBM50400539 CHEMBL2204952

SMILES COc1ccc(CNC(=O)N[C@@H](CC(C)C)C(=O)NO)cc1

InChI Key InChIKey=AHEQYFRNVZSMPY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50400539   

TargetAminopeptidase N(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50400539(CHEMBL2204952)
Affinity DataIC50: 830nMAssay Description:Inhibition of APN in porcine kidney microsome assessed as inhibition of L-Leu-p-nitroanilide substrate hydrolysis incubated for 5 mins before substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50400539(CHEMBL2204952)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of APN in human ES2 cell surface assessed as inhibition of L-Leu-p-nitroanilide substrate hydrolysis incubated for 5 mins before substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50400539(CHEMBL2204952)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of recombinant MMP-2 using succinylated gelatin as substrate incubated for 10 mins before addition of substrate measured after 60 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed