BDBM50400712 CHEMBL2204246

SMILES COc1ncc(cc1C)[C@]1(O)CC[C@@H](CC1)N1CC(C1)NC(=O)CNC(=O)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=YCUKJXACAKDNPS-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50400712   

TargetC-C chemokine receptor type 2(Human)
TBA

Curated by ChEMBL

LigandBDBM50400712(CHEMBL2204246)Copy SMILESCopy InChI

Affinity DataIC50: 220nMAssay Description:Displacement of [125I]-MCP-1 from CCR2 in human THP-1 cells after 2 hrs by microplate scintillation and luminescence counter analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetPotassium voltage-gated channel subfamily H member 2(Human)
TBA

Curated by ChEMBL

LigandBDBM50400712(CHEMBL2204246)Copy SMILESCopy InChI

Affinity DataIC50: 2.16E+4nMAssay Description:Displacement of [3H]-astemizole from human ERG expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL