BDBM50400824 CHEMBL2204342

SMILES COc1ccc(cc1)[C@@H](CN(C)C)[Si]1(O)CCCCC1

InChI Key InChIKey=KIXBFSFRCBHKLN-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50400824   

TargetSodium-dependent dopamine transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50400824(CHEMBL2204342)
Affinity DataIC50: 3.64E+4nMAssay Description:Inhibition of DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50400824(CHEMBL2204342)
Affinity DataIC50: 4.72E+3nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50400824(CHEMBL2204342)
Affinity DataIC50: 791nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50400824(CHEMBL2204342)
Affinity DataIC50: 3.64E+4nMAssay Description:Inhibition of human DAT expressed in CHOK1 cells assessed as decrease in [3H]-dopamine reuptake after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50400824(CHEMBL2204342)
Affinity DataIC50: 791nMAssay Description:Inhibition of human SERT expressed in HEK293 cells assessed as decrease in [3H]-serotonin reuptake after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50400824(CHEMBL2204342)
Affinity DataIC50: 4.72E+3nMAssay Description:Inhibition of human NET expressed in MDCK cells assessed as decrease in [3H]-noradrenaline reuptake after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed