BDBM50401097 CHEMBL2204469

SMILES Cc1c(Cc2ccc(=O)n(Cc3ccc(F)cc3F)n2)c2cc(F)ccc2n1CC(O)=O

InChI Key InChIKey=ZTPOWDSDKMQVBU-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50401097   

TargetProstaglandin D2 receptor 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human recombinant CRTh2 expressed in CHO-K1 cells by cAMP TR FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of CRTH2 receptor-mediated chemotaxis in human basophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of CYP2A6More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50: 0.800nMAssay Description:Binding affinity to human CRTH2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]PGD2 from recombinant human CRTH2 receptor expressed in CHO-K1 cells after 30 min by FRET methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50: 1.90E+4nMAssay Description:Binding affinity to DP1 receptor by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50: 7nMAssay Description:Inhibition of mouse CRTH2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of CYP2B6More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of CYP2C8More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50: 5.60E+5nMAssay Description:Antagonist activity at TXA2 receptor by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed