BDBM50401289 CHEMBL2204529

SMILES CC(=O)Nc1nc2cnc(Nc3cc(NC(=O)c4cccc(c4Cl)C4(CC4)C#N)ccc3C)nc2s1

InChI Key InChIKey=XCAXPNXUNVKBEX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50401289   

TargetVascular endothelial growth factor receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50401289(CHEMBL2204529)
Affinity DataIC50: 340nMAssay Description:Inhibition of VEGFR2 in HUVEC assessed as reduction of VGF-stimulated cell proliferation after 5 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed