BDBM50402410 CHEMBL2207760

SMILES CCN1CCC[C@@H]1C(=O)Nc1ccc(cc1)-c1ccnc(Nc2ccc(cc2)N2CCOCC2)n1

InChI Key InChIKey=HKCCVEZCHYRSPJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50402410   

TargetTyrosine-protein kinase JAK2(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402410(CHEMBL2207760)
Affinity DataIC50: 2.17E+3nMAssay Description:Inhibition of JAK2 in HEL 92.1.7 cells assessed as inhibition of STAT3 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402410(CHEMBL2207760)
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of JAK2 in HEL 92.1.7 cells assessed as inhibition of STAT1 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402410(CHEMBL2207760)
Affinity DataIC50: 557nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402410(CHEMBL2207760)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed