BDBM50402490 CHEMBL2204051

SMILES O=c1[nH]c([C@@H]2CC[C@@H](CC2)c2ccccc2)c(Cc2ncccn2)c(=O)[nH]1

InChI Key InChIKey=FHWVHJREWMBQJT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50402490   

TargetGlucocorticoid receptor(Human)
Corcept Therapeutics

Curated by ChEMBL
LigandPNGBDBM50402490(CHEMBL2204051)
Affinity DataKi:  400nMAssay Description:Displacement of [3H]dexamethasone from human recombinant glucocorticoid receptor expressed in baculovirus after 18 hrs by scintillation counting anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Corcept Therapeutics

Curated by ChEMBL
LigandPNGBDBM50402490(CHEMBL2204051)
Affinity DataKi: >3.00E+3nMAssay Description:Antagonist activity at glucocorticoid receptor in human SW1353 cells assessed as inhibition of dexamethasone-induced luciferase expression after 16 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed