BDBM50402821 CHEMBL2208435

SMILES O[C@H](CNC(=O)c1cnnc2ccccc12)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1

InChI Key InChIKey=KOUMCBHTVFDPSI-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50402821   

LigandPNGBDBM50402821(CHEMBL2208435)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of human ERG in HEK cells by ion flux electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50402821(CHEMBL2208435)
Affinity DataKi:  12.6nMAssay Description:Displacement of [3H]-pyrilamine from human histamine H1 receptor expressed in recombinant CHOK1 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50402821(CHEMBL2208435)
Affinity DataKi:  12.6nMAssay Description:Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4- (methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed