BDBM50403054 CHEMBL2216825

SMILES C[C@H]1O[C@H](C[C@H]([C@@H]1O)N(C)C)c1ccc2C(=O)C3=C([C@@H](C)O[C@@H]4CC(=O)O[C@H]34)C(=O)c2c1O

InChI Key InChIKey=NYJGMJFBEVSQNN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50403054   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50403054(CHEMBL2216825)
Affinity DataIC50: 149nMAssay Description:Inhibition of AKT1 (unknown origin) by high-throughput screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50403054(CHEMBL2216825)
Affinity DataIC50: 149nMAssay Description:Inhibition of human AKT1 using biotinylated GSKalpha peptide (SGRARTSSFA) as a substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50403054(CHEMBL2216825)
Affinity DataIC50: 11nMAssay Description:Inhibition of ROCK2 (unknown origin) using SKT S2 as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed