BDBM50403553 CHEMBL5266739

SMILES Clc1ccc(cc1)-c1[nH]ncc1C(=O)Nc1cccc(c1)S(=O)(=O)N1CCCCC1

InChI Key InChIKey=LIKPCUYPZUOYKD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50403553   

TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandPNGBDBM50403553(CHEMBL5266739)
Affinity DataIC50: 520nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF11(Human)
Amgen Research

Curated by ChEMBL
LigandPNGBDBM50403553(CHEMBL5266739)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant GST-tagged human Eg5 assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Amgen Research

Curated by ChEMBL
LigandPNGBDBM50403553(CHEMBL5266739)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant GST-tagged human CENP-E assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed