BDBM50403661 CHEMBL4170411

SMILES CCNC(=O)c1noc(c1-c1ccc(CNCC(=O)Nc2ccc(OC)c(Nc3ncc(Cl)c(Nc4ccccc4S(=O)(=O)C(C)C)n3)c2)cc1)-c1cc(C(C)C)c(O)cc1O

InChI Key InChIKey=FGPCDMAFJXAZGK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50403661   

TargetALK tyrosine kinase receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403661(CHEMBL4170411)
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant ALK (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403661(CHEMBL4170411)
Affinity DataIC50: 260nMAssay Description:Inhibition of FITC-labeled geldanamycin binding to recombinant HSP90alpha (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed