BDBM50404028 CHEMBL2021376

SMILES Nc1nc2c(nc(N)[nH]c2=O)n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

InChI Key InChIKey=FNXPTCITVCRFRK-UHFFFAOYSA-N

Data  6 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50404028   

TargetPurine nucleoside phosphorylase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50404028(CHEMBL2021376)
Affinity DataIC50: 1.40E+3nMAssay Description:Compound was tested for inhibition of purine nucleoside phosphorylase using human erythro lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50404028(CHEMBL2021376)
Affinity DataIC50: 1.33E+3nMAssay Description:Compound was evaluated for 50% inhibition of purine nucleoside phosphorylase activity by was measured by the conversion of [8-14C]-inosine to [8-14C]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50404028(CHEMBL2021376)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity against Purine nucleoside phosphorylase evaluated by radiochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50404028(CHEMBL2021376)
Affinity DataIC50: 1.40E+3nMAssay Description:Ability to inhibit purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50404028(CHEMBL2021376)
Affinity DataKi:  7.00E+3nMAssay Description:Compound was evaluated for the inhibitory activity against PNP activity in dialyzed extracts from human erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50404028(CHEMBL2021376)
Affinity DataKi:  7.00E+3nMAssay Description:Compound was evaluated for its binding affinity against human erythrocyte purine nucleoside phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50404028(CHEMBL2021376)
Affinity DataKi:  1.70E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPurine nucleoside phosphorylase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50404028(CHEMBL2021376)
Affinity DataKi:  2.00E+5nMAssay Description:Compound was evaluated for its binding affinity against Toxoplasma gondii purine nucleoside phosphorylase of virulent strain RH (value indicates comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50404028(CHEMBL2021376)
Affinity DataKi:  2.90E+5nMAssay Description:Competitive inhibition of human erythrocyte purine nucleoside phosphorylase assessed as inhibition of guanosine phosphorylysis after 30 mins by Linew...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50404028(CHEMBL2021376)
Affinity DataKi:  2.00E+5nMAssay Description:Compound was evaluated for its binding affinity against Toxoplasma gondii purine nucleoside phosphorylase from cystic strain ME 49 (value indicates c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed