BDBM50404381 CHEMBL5274740

SMILES COc1ccc(Oc2ccc(cc2)N(Cc2ccccc2)C(=O)CCl)cc1

InChI Key InChIKey=DPADEQNOMBTITM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50404381   

TargetE3 ubiquitin-protein ligase RNF4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50404381(CHEMBL5274740)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant RNF4 incubated for 30 mins by SDS-PAGE based densitometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase RNF4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50404381(CHEMBL5274740)
Affinity DataIC50: 1.80E+3nMAssay Description:Binding affinity to RNF4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase RNF4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50404381(CHEMBL5274740)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of IA-rhodamine-labeled human RNF4 preincubated for 30 mins followed by IA-rhodamine addition for 1 hr by gel-based ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed