BDBM50404476 CHEMBL4169913

SMILES Cc1c(nc2cccnc2c1-c1ccccc1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=PQXHRLBMQBCMER-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50404476   

TargetDNA topoisomerase 1(Human)
Universidad De Le£N

Curated by ChEMBL
LigandPNGBDBM50404476(CHEMBL4169913)
Affinity DataIC50: 7.06E+4nMAssay Description:Inhibition of human Top1B expressed in Top1B deficient Saccharomyces cerevisiae EKY3 assessed as decrease in relaxation of supercoiled pSK DNA preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed