BDBM50405800 CHEMBL5267207

SMILES O=C(Nc1nnn[nH]1)C1C2C=CC=CC2Oc2ccccc12

InChI Key InChIKey=MEFDXVJUTKLMFA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50405800   

TargetNADP-dependent malic enzyme, mitochondrial(Human)
Sun Pharma Advanced Research Company

Curated by ChEMBL
LigandPNGBDBM50405800(CHEMBL5267207)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of His-tagged human recombinant ME3 (26 to 604 residues) using L-malate and beta-NADP+ as substrate preincubated with enzyme for 5 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetNAD-dependent malic enzyme, mitochondrial(Human)
Sun Pharma Advanced Research Company

Curated by ChEMBL
LigandPNGBDBM50405800(CHEMBL5267207)
Affinity DataIC50: 200nMAssay Description:Inhibition of His-tagged human recombinant full length ME2 using L-malate and beta-NAD+ as substrate preincubated with enzyme for 5 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetNADP-dependent malic enzyme(Human)
Sun Pharma Advanced Research Company

Curated by ChEMBL
LigandPNGBDBM50405800(CHEMBL5267207)
Affinity DataIC50: 220nMAssay Description:Inhibition of His-tagged human recombinant full length ME1 using L-malate and beta-NADP+ as substrate preincubated with enzyme for 5 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed