BDBM50405821 CHEMBL5281258

SMILES COCCOc1ccc(CCC(=O)N2CCN(CC2)c2ccc(O)cn2)cc1

InChI Key InChIKey=JWUVROKCRSMKBC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50405821   

TargetNADP-dependent malic enzyme, mitochondrial(Human)
Sun Pharma Advanced Research Company

Curated by ChEMBL
LigandPNGBDBM50405821(CHEMBL5281258)
Affinity DataIC50: 580nMAssay Description:Inhibition of His-tagged human recombinant ME3 (26 to 604 residues) using L-malate and beta-NADP+ as substrate preincubated with enzyme for 5 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetNAD-dependent malic enzyme, mitochondrial(Human)
Sun Pharma Advanced Research Company

Curated by ChEMBL
LigandPNGBDBM50405821(CHEMBL5281258)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of His-tagged human recombinant full length ME2 using L-malate and beta-NAD+ as substrate preincubated with enzyme for 5 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetNADP-dependent malic enzyme(Human)
Sun Pharma Advanced Research Company

Curated by ChEMBL
LigandPNGBDBM50405821(CHEMBL5281258)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of His-tagged human recombinant full length ME1 using L-malate and beta-NADP+ as substrate preincubated with enzyme for 5 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed