BDBM50405826 CHEMBL5290463

SMILES Oc1ccc(nc1)N1CCN(CC1)C(=O)CCc1ccc(s1)-c1ccccc1

InChI Key InChIKey=NMCOMGYGVBTNMG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50405826   

TargetNADP-dependent malic enzyme, mitochondrial(Human)
Sun Pharma Advanced Research Company

Curated by ChEMBL
LigandPNGBDBM50405826(CHEMBL5290463)
Affinity DataIC50: 250nMAssay Description:Inhibition of His-tagged human recombinant ME3 (26 to 604 residues) using L-malate and beta-NADP+ as substrate preincubated with enzyme for 5 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetNAD-dependent malic enzyme, mitochondrial(Human)
Sun Pharma Advanced Research Company

Curated by ChEMBL
LigandPNGBDBM50405826(CHEMBL5290463)
Affinity DataIC50: 1.97E+3nMAssay Description:Inhibition of His-tagged human recombinant full length ME2 using L-malate and beta-NAD+ as substrate preincubated with enzyme for 5 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetNADP-dependent malic enzyme(Human)
Sun Pharma Advanced Research Company

Curated by ChEMBL
LigandPNGBDBM50405826(CHEMBL5290463)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of His-tagged human recombinant full length ME1 using L-malate and beta-NADP+ as substrate preincubated with enzyme for 5 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed