BDBM50406825 CHEMBL4161994

SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(Oc2c1)c1ccccc1F

InChI Key InChIKey=CBMLEDNBJXYMIV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50406825   

TargetBromodomain-containing protein 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50406825(CHEMBL4161994)
Affinity DataIC50: 570nMAssay Description:Inhibition of His6-tagged human BRD4 bromodomain-1 (N44 to E168 residues) expressed in Escherichia coli BL21(DE3) using biotinylated-H4KAc4 as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50406825(CHEMBL4161994)
Affinity DataIC50: 2.47E+3nMAssay Description:Inhibition of His6-tagged human CREBBP (R1081 to G1197 residues) expressed in Escherichia coli BL21(DE3) using biotinylated-H4KAc4 as substrate by Al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed