BDBM50407424 CHEMBL5273541

SMILES CCN1CC(=O)N2[C@H](Cc3c([nH]c4ccccc34)[C@H]2c2ccc(Cl)cc2)C1=O

InChI Key InChIKey=HVAXOHCNVYSJEB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50407424   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Univ. Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50407424(CHEMBL5273541)
Affinity DataIC50: 3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Univ. Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50407424(CHEMBL5273541)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant PDE5A using (Fl)-cAMP and TAMRA-cGMP as substrate incubated for 60 mins by IMAP-fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed