BDBM50407427 CHEMBL5275356

SMILES [H][C@@]12Cc3c([nH]c4ccccc34)[C@H](N1C(=O)CN(CCC1CCN(Cc3ccccc3)CC1)C2=O)c1ccc(OC)cc1

InChI Key InChIKey=NGKJYYMHPLWVQZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50407427   

TargetAcetylcholinesterase(Human)
Univ. Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50407427(CHEMBL5275356)
Affinity DataIC50: 15nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Univ. Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50407427(CHEMBL5275356)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Univ. Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50407427(CHEMBL5275356)
Affinity DataIC50: 15nMAssay Description:Inhibition of PDE5A1 (unknown origin) using FAM-cGMP as substrate incubated for 60 mins by IMAP-fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Rat)
Rural Federal University of Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50407427(CHEMBL5275356)
Affinity DataIC50: 3.23E+3nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate incubated for 20 mins by DTNB-reagent based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Univ. Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50407427(CHEMBL5275356)
Affinity DataIC50: 3.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Univ. Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50407427(CHEMBL5275356)
Affinity DataIC50: 3.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed