BDBM50407428 CHEMBL5288859

SMILES CCc1nnc2c3ccccc3nc(Nc3cccc(c3)C(O)=O)n12

InChI Key InChIKey=INDKHRIZOIEPIG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50407428   

TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Human)
Rural Federal University of Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50407428(CHEMBL5288859)
Affinity DataIC50: 280nMAssay Description:Inhibition of PDE8A (unknown origin) using cAMP as substrate incubated for 30 mins by Ba(OH)2 precipitation assay based scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Rural Federal University of Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50407428(CHEMBL5288859)
Affinity DataIC50: 220nMAssay Description:Inhibition of PDE4A (unknown origin) using cAMP as substrate incubated for 30 mins by Ba(OH)2 precipitation assay based scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed