BDBM50408961 CHEMBL4170576

SMILES CN(CC(O)CCOc1ccc(F)cc1)Cc1c(C)nn(Cc2ccccc2Cl)c1C

InChI Key InChIKey=JZOBOJVGFIIVSE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50408961   

TargetToll-like receptor 4(Human)
School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50408961(CHEMBL4170576)
Affinity DataIC50: 5.54E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed