BDBM50409203 CHEMBL5289038

SMILES CC1(C)C(N(Cc2ccc(cc2)C(=O)NO)c2ccccc12)c1ccncc1

InChI Key InChIKey=WOTUHAJNRNHMHC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50409203   

TargetHistone deacetylase 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50409203(CHEMBL5289038)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of human recombinant HDAC1 using ZMAL (Z-(Ac)Lys-AMC) as fluorogenic substrate incubated for 120 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50409203(CHEMBL5289038)
Affinity DataIC50: 61nMAssay Description:Inhibition of human recombinant HDAC6 using ZMAL (Z-(Ac)Lys-AMC) as fluorogenic substrate incubated for 120 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50409203(CHEMBL5289038)
Affinity DataIC50: 4.64E+3nMAssay Description:Inhibition of human recombinant HDAC8 using FLUOR DE LYS fluorometric substrate pre-incubated for 15 mins and followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed