BDBM50410792 CHEMBL5272587

SMILES Cn1nc(cc1C(C)(C)O)C1NN(C2CCCN(C2)C(=O)C=C)c2ncnc(N)c12

InChI Key InChIKey=NNJYOOTXCWAFKM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50410792   

TargetTyrosine-protein kinase JAK2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50410792(CHEMBL5272587)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human JAK2 using biotin as a substrate preincubated for 5 mins followed by substrate addition incubated for 30 mins in presence of ATP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50410792(CHEMBL5272587)
Affinity DataIC50: 8nMAssay Description:Inhibition of human BTK using biotin as a substrate preincubated for 5 mins followed by substrate addition incubated for 30 mins in presence of ATP b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed