BDBM50410841 CHEMBL5266767

SMILES FC(F)(F)c1ccc(NC(=O)Nc2ccc(Oc3ccc(cc3)C(=O)c3ncc[nH]3)cc2)cc1Cl

InChI Key InChIKey=ZHZNMLSEHSKXHB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50410841   

TargetSerine/threonine-protein kinase B-raf(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50410841(CHEMBL5266767)
Affinity DataIC50: 86nMAssay Description:Inhibition of full length human BRAF V600E mutant using His-tagged full length human MEK1 (K97R) as substrate incubated for 20 mins by [gamma-33P]ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50410841(CHEMBL5266767)
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using Fluor-de-Lys as substrate incubated for 10 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed