BDBM50411229 CHEMBL450667

SMILES Clc1cc(cnc1Cl)N1C[C@H]2CCNC[C@@H]12

InChI Key InChIKey=VXCWOKWPZDBULP-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50411229   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50411229(CHEMBL450667)
Affinity DataEC50:  176nMAssay Description:Agonist activity at human alpha4beta2 ACHR expressed in HEK293 cells assessed as change in intracellular calcium concentration by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Burnham Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50411229(CHEMBL450667)
Affinity DataEC50:  178nMAssay Description:Agonist activity against human alpha4beta2 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Burnham Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50411229(CHEMBL450667)
Affinity DataEC50:  339nMAssay Description:Agonist activity against human alpha3beta4 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed