BDBM50412131 CHEMBL522708

SMILES Cc1ccc2c(OCCN3CCC(Cc4cccc(c4)N4CCCS4(=O)=O)CC3)cccc2n1

InChI Key InChIKey=WQRVLZPCOXHNAI-UHFFFAOYSA-N

Data  17 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50412131   

Target5-hydroxytryptamine receptor 1D(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412131(CHEMBL522708)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]5HT from human recombinant 5HT1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412131(CHEMBL522708)
Affinity DataKi:  7.90nMAssay Description:Displacement of [3H]WAY100635 from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412131(CHEMBL522708)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]5HT from human recombinant 5HT1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412131(CHEMBL522708)
Affinity DataKi:  16nMAssay Description:Displacement of radioligand from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412131(CHEMBL522708)
Affinity DataKi:  158nMAssay Description:Displacement of radioligand from human cloned adrenergic Alpha-1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412131(CHEMBL522708)
Affinity DataKi:  398nMAssay Description:Displacement of radioligand from human cloned SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412131(CHEMBL522708)
Affinity DataKi:  501nMAssay Description:Displacement of radioligand from human cloned dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412131(CHEMBL522708)
Affinity DataKi:  794nMAssay Description:Inhibition of [3H]5HT uptake at SERT in rat cortical synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412131(CHEMBL522708)
Affinity DataKi: <1.00E+3nMAssay Description:Displacement of radioligand from human cloned 5HT2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412131(CHEMBL522708)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of radioligand from human cloned 5HT1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412131(CHEMBL522708)
Affinity DataKi:  1.59E+3nMAssay Description:Displacement of radioligand from human cloned 5HT5A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412131(CHEMBL522708)
Affinity DataKi:  1.59E+3nMAssay Description:Displacement of radioligand from human cloned 5HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412131(CHEMBL522708)
Affinity DataKi:  1.59E+3nMAssay Description:Displacement of radioligand from human cloned adrenergic beta2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412131(CHEMBL522708)
Affinity DataKi: <3.98E+3nMAssay Description:Displacement of radioligand from human cloned 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412131(CHEMBL522708)
Affinity DataKi: <6.31E+3nMAssay Description:Displacement of radioligand from human cloned 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412131(CHEMBL522708)
Affinity DataKi:  7.94E+3nMAssay Description:Displacement of radioligand from human cloned 5HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1E(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412131(CHEMBL522708)
Affinity DataKi: <1.00E+4nMAssay Description:Displacement of radioligand from human cloned 5HT1E receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed