BDBM50412615 CHEMBL465920

SMILES Nc1c(cnn1-c1ccc(F)cc1)C(=O)NCC(O)(CNC(=O)c1c(F)cccc1F)C(F)(F)F

InChI Key InChIKey=PJQIOELKQZILCS-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50412615   

TargetGlucocorticoid receptor(Human)
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50412615(CHEMBL465920)
Affinity DataIC50: 398nMAssay Description:Displacement of fluorescent labelled Dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50412615(CHEMBL465920)
Affinity DataEC50: >6.31E+3nMAssay Description:Agonist activity at human glucocorticoid receptor in human A549 cells assessed as transcriptional activity by MMTV luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed