BDBM50414327 CHEMBL128537

SMILES [O-][N+](=O)c1cccc(c1)-c1ccc(OCC(CCc2ccncc2)N2CCCCC2=O)cc1

InChI Key InChIKey=NRDKFCWQKJPTEO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50414327   

TargetP2X purinoceptor 7(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414327(CHEMBL128537)
Affinity DataIC50: 6.31E+3nMAssay Description:In vitro antagonism of P2X 7 receptor in THP-1 (human pre-monocytic) cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414327(CHEMBL128537)
Affinity DataIC50: 6.31E+3nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed