BDBM50414692 CHEMBL557867

SMILES COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CCCCCN2C(=O)c3ccccc3C2=O)CC1

InChI Key InChIKey=LYBOUGULDAGMCU-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50414692   

Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandPNGBDBM50414692(CHEMBL557867)
Affinity DataEC50:  5.01nMAssay Description:Agonist activity at human 5HT4C receptor expressed in HEK293 cells assessed as accumulation of cAMP by flash plate adenylyl cyclase activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandPNGBDBM50414692(CHEMBL557867)
Affinity DataKi:  19.9nMAssay Description:Displacement of [H]GR-113808 from human 5HT4C receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed