BDBM50414755 CHEMBL2094007

SMILES CC(C)c1onc(c1COc1ccc2[nH]cc(Cc3cccc(c3)C(O)=O)c2c1)-c1c(Cl)cccc1Cl

InChI Key InChIKey=OUUIEEORVJIONR-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50414755   

TargetBile acid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50414755(CHEMBL2094007)
Affinity DataEC50:  1.50E+3nMAssay Description:Induction of SRC1 coactivator peptide binding to ligand binding domain of human FXR by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50414755(CHEMBL2094007)
Affinity DataEC50: >1.00E+4nMAssay Description:Increase in human FXR-mediated transient transcription of luciferase reporter gene transfected in african green monkey CV1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed