BDBM50415882 CHEMBL1094106

SMILES Cc1n[nH]c(C)c1CC(=O)NCc1ccc(F)cc1Cl

InChI Key InChIKey=VLTURVHREGNKGZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50415882   

TargetP2X purinoceptor 7(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415882(CHEMBL1094106)
Affinity DataIC50: 19.9nMAssay Description:Inhibition of human P2X7 receptor assessed as inhibition of ethidium bromide accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415882(CHEMBL1094106)
Affinity DataIC50: 19.9nMAssay Description:Antagonist activity at human P2X7 receptor ethidium bromide release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415882(CHEMBL1094106)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415882(CHEMBL1094106)
Affinity DataIC50: 158nMAssay Description:Inhibition of rat P2X7 receptor assessed as inhibition of ethidium bromide accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415882(CHEMBL1094106)
Affinity DataIC50: 158nMAssay Description:Antagonist activity at rat P2X7 receptor ethidium bromide release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed