BDBM50416077 CHEMBL1086115

SMILES CCN(c1ccccc1)S(=O)(=O)c1ccc(-c2ccc3n(ncc3c2)-c2ccc(F)cc2)c(c1)C(F)(F)F

InChI Key InChIKey=UGEICSSTWXHBRN-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50416077   

TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416077(CHEMBL1086115)
Affinity DataIC50: 15.8nMAssay Description:Displacement of fluorescent-labeled Dexamethasone from GR by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416077(CHEMBL1086115)
Affinity DataIC50: 126nMAssay Description:Activity at GR in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416077(CHEMBL1086115)
Affinity DataEC50:  200nMAssay Description:Agonist activity at GR in human A549 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416077(CHEMBL1086115)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to PRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416077(CHEMBL1086115)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed