BDBM50416079 CHEMBL1084716

SMILES CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(=O)(=O)Nc1ccc(-c2ccc3n(ncc3c2)-c2ccc(F)cc2)c(c1)C(F)(F)F

InChI Key InChIKey=LLVIFFLKXVFNND-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50416079   

TargetProgesterone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416079(CHEMBL1084716)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to PRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416079(CHEMBL1084716)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416079(CHEMBL1084716)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at GR in human A549 cells transfected with luciferase gene linked to MMTV promoter assessed as inhibition of dexamethasone-induce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416079(CHEMBL1084716)
Affinity DataIC50: 1.00E+4nMAssay Description:Activity at GR in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416079(CHEMBL1084716)
Affinity DataIC50: 251nMAssay Description:Displacement of fluorescent-labeled Dexamethasone from GR by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed