BDBM50416095 CHEMBL1086311

SMILES Fc1ccc(cc1)-n1ncc2cc(ccc12)-c1ccccc1C#N

InChI Key InChIKey=VUTMSTDGJXSCFU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50416095   

TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416095(CHEMBL1086311)
Affinity DataIC50: 398nMAssay Description:Displacement of fluorescent-labeled Dexamethasone from GR by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416095(CHEMBL1086311)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416095(CHEMBL1086311)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to PRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416095(CHEMBL1086311)
Affinity DataIC50: 1.00E+4nMAssay Description:Activity at GR in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed