BDBM50416101 CHEMBL1082780

SMILES Fc1ccc(cc1)-n1ncc2cc(ccc12)-c1ccc(NS(=O)(=O)c2ccsc2)cc1C(F)(F)F

InChI Key InChIKey=YDGNXSOLWOOFRO-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50416101   

TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416101(CHEMBL1082780)
Affinity DataIC50: 12.6nMAssay Description:Displacement of fluorescent-labeled Dexamethasone from GR by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416101(CHEMBL1082780)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to PRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416101(CHEMBL1082780)
Affinity DataIC50: 2.51E+3nMAssay Description:Binding affinity to ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416101(CHEMBL1082780)
Affinity DataEC50:  251nMAssay Description:Agonist activity at GR in human A549 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416101(CHEMBL1082780)
Affinity DataIC50: 100nMAssay Description:Activity at GR in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed