BDBM50416868 CHEMBL1257453

SMILES CC(C)(CC(O)(CNc1cccc2ncccc12)C(F)(F)F)c1cc(F)ccc1O

InChI Key InChIKey=BCEBCGJPCPOGCH-UHFFFAOYSA-N

Data  6 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50416868   

TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50416868(CHEMBL1257453)
Affinity DataIC50: 1nMAssay Description:Binding affinity to human recombinant glucocorticoid receptor expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50416868(CHEMBL1257453)
Affinity DataIC50: 6.31nMAssay Description:Transrepression activity at glucocorticoid receptor-mediated antiinflammatory activity in human HeLa cells assessed as inhibition of TPA-induced coll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50416868(CHEMBL1257453)
Affinity DataIC50: 19.9nMAssay Description:Transrepression activity at glucocorticoid receptor-mediated antiinflammatory activity in human THP1 cells assessed as inhibition of LPS-induced IL-8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50416868(CHEMBL1257453)
Affinity DataEC50:  79.4nMAssay Description:Transactivation activity at glucocorticoid receptor in human HeLa cells assessed as induction of MMTV promoter activity by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50416868(CHEMBL1257453)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to human recombinant androgen receptor expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50416868(CHEMBL1257453)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to human recombinant progesterone receptor expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50416868(CHEMBL1257453)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to human recombinant mineralocorticoid receptor expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed