BDBM504174 N-(2,2-Dimethyl-6-(4-((4- methylthiazol-5- yl)methyl)piperazin-1-yl)-2,3- dihydrobenzofuran-5- yl)pyrazolo[1,5-a]pyrimidine-3- carboxamide::US11034698, Example 11

SMILES Cc1ncsc1CN1CCN(CC1)c1cc2OC(C)(C)Cc2cc1NC(=O)c1cnn2cccnc12

InChI Key InChIKey=TURRHMVSVDSHDB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 504174   

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM504174(N-(2,2-Dimethyl-6-(4-((4- methylthiazol-5- yl)meth...)
Affinity DataKi:  4.60nMAssay Description:The IRAK4 reaction conditions were optimized using an IRAK1-derived peptide (sequence H-KKARFSRFAGSSPSQSSMVAR) to provide a linear reaction rate over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent